The web portal answers important questions about the Covid-19 vaccines. It puts together the latest information on the effect, functioning, development and approval of the vaccines.

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How effective are the approved mRNA vaccines?

In the studies for approval, the mRNA vaccines from Pfizer/BionTech and Moderna demonstrated an effectiveness against infection with Covid-19 of over 90 percent.

However, against the Omicron variant of Covid-19, which currently dominates in Switzerland, the protective effect against infection appears to be reduced. In contrast, the mRNA vaccines still offer a high level of protection against a severe course of disease, including against Omicron.

Protection from vaccination declines over time. Especially in older persons. A booster vaccination helps to increase the effectiveness again. The booster vaccination protects against severe infection for at least 6-9 months.

Since August 2022, a booster vaccine from Moderna adapted to Omicron has been authorized in Switzerland (Spikevax® Bivalent Original/Omicron (mRNA-1273.214)). In studies, this vaccine resulted in a stronger immune response against the Omicron variant (subvariants BA.1 and BA.4/5) than the original vaccine. It is not yet known whether the adapted vaccine also provides better protection against infection and a severe course of disease caused by Omicron, and how long the protection lasts.